2022

ACTI-RESEARCH AND INNOVATION LECTURES

3D cell cultures for pharmaceutical research: challenges, technologies, and solutions

12:00 h

There is a consistent interest in applying 3D cell culture models for pharmacological research and drug screening. However, evident technological hurdles that are due to the three-dimensional design of the models have to be addressed. These range from the establishment of the appropriate model system for a given purpose, the need for making the tested models amenable for acute drug testing, as well as for whole mount staining and imaging, the choice of appropriate markers for morphological, functional, and molecular assessment of drug effects, and the quantitative analysis of the retrieved data.

This presentation gives an overview on achievements within M2Aind that are pertinent to these challenges.
 
Lecturer:
 
Prof. Rüdiger Rudolf, Research Group Leader, Institute for Molecular and Cell Biology, Faculty of Biotechnology, Mannheim University of Applied Sciences

Join Zoom Meeting: https://lnkd.in/eFUc7e8H

Organized by: https://www.um.es/

BioRN Lounge

Solutions for the health industry at the interface between academia and industry in the Rhein-Main-Neckar Region

With Rüdiger Rudolf

Mannheim University of Applied Sciences Center for Mass Spectrometry and Optical Spectroscopy (CeMOS) &
Interdisciplinary Center for Neurosciences (IZN), Heidelberg University

Learn about solutions for the health industry at the interface between academia and industry in the Rhein-Main-Neckar Region by CeMOS - Center for Mass Spectrometry and Optical Spectroscopy and M²Aind - Multimodal analytics and intelligent sensors for Hochschule Mannheim.

​Please register: https://www.biorn.org/biorn-lounge

BioRN Lounge

Solutions for the health industry at the interface between academia and industry in the Rhein-Main-Neckar Region

With Carsten Hopf

Head, Center for Mass Spectrometry and Optical Spectroscopy (CeMOS)
Spokesperson M2Aind, Partnership for Innovation in Health Industry
Associated Prof. Medical Faculty, Heidelberg University


The Center for Mass Spectrometry and Optical Spectroscopy (CeMOS) co-creates integrated solutions (devices, chemicals, applications and information technology) with a network of >100 SMEs, with leading academics and with many (inter)nationally well-known companies in biomedicine, IT and beyond. Among other assets, CeMOS operates the Rhine-Neckar-Center for Mass spectrometry imaging and assays and a Leica Imaging reference center for joint projects with industry and academia. CeMOS also orchestrates the partnership for innovation “Multimodal Analytics for the Health Industry” (M2Aind) to promote innovative research and industry transfer in digital technology for (bio)pharma, #chemical, and food #production and to further develop a multimodal platform for drug discovery research.

Register now:
https://lnkd.in/eSdFdUev

2021

Agile Falcon Strategic Group’s

Referent: Prof. Dr. Carsten Hopf

Juni 8, 2021

DDSS organisiert von PPSC: 7th Drug Discovery Strategic Summit

Vortrag: Mass spectrometry imaging in pharma R&D

Referent: Prof. Dr. Carsten Hopf

Mai 28, 2021

Bruker Virtual Event: Pharmaceutical applications with Trapped Ion Mobility Mass Spectrometry

Droplet Microarrays - Readout by MALDI imaging

Referent: Prof. Dr. Carsten Hopf

Mai 25, 2021

Bruker Webinar mit Pavel Levkin, KIT

Vortrag: Development of an automated MALDI MS assay for direct analysis of cellular drug uptake via OATP2B1

Referent: Dr. Melissa Unger (AG Prof. Dr. Carsten Hopf)

Januar 25, 2021

SLAS Europe 2021 - SelectScience

2020

Vortrag: Infrared Spectroscopy-guided Mass Spectrometry

Referent: Prof. Dr. Carsten Hopf

November 22, 2019

COMULIS COST Action & Bioimanging Austria - CMI Conference, Vienna

Vortrag: MALDI-MS-based assays for cellular drug action and transport with rapifleX MPP

Referent: Dr. Melissa Unger (AG Prof. Dr. Carsten Hopf)

November 18, 2020

Webinar der Firma Bruker

2019

Vortrag: Sphäroide / Organoide / 3D Zellkultur

Referent: Prof. Dr. Rüdiger Rudolf

Journal Club

Vortrag: (i) Aroma profiling of brewing hops by ion mobility spectrome-try and modern signal processing (ii) Data fusion of GC-IMS data and FT-MIR spectra for the au-thentication of olive oils and honeys – is it worth to go the extra mile?

Referent: Prof. Dr. Philipp Weller 

November 5-8, 2019

Recent Advances in Food Analysis (RAFA), Prague

Vortrag: Applications of MS Imaging in Pharmaceutical R&D

Referent: Prof. Dr. Carsten Hopf

Oktober 29, 2019

OurCon VII, Global Mass Spectrometry Imaging Conference, St. Malo, France

Vortrag: Optical, Molecular Sensitive, Imaging Monitoring Techniques and Applications in the Micro-channel

Referent: Prof. Dr. Matthias Rädle

Oktober 24, 2019

ISTEGIM 2019, Ettlingen

Vortrag: "Mass Spectrometry Imaging and Fingerprinting of Metabolites in Drug Discovery and (Pre)Clinical Studies"

Referent: Prof. Dr. Carsten Hopf

Heidelberg Metabolomics Symposium 2019 - Metabolomics in Cancer and Diabetes Research

Vortrag: "Einsatz von COMSOL in der Chemischen Technik"

Referent: Prof. Dr. Thorsten Röder

COMSOL Days

Vortrag: "Ultraschnelle lokale Ramanmessung zur Untersuchung von Mischvorgängen in Mikroreaktoren"

Referent: Prof. Dr. Matthias Rädle, Teammitglieder: J. Deuerling, S. Keck, F. Braun, M. Nachtmann, T. Hufnagel, L. Schmitt, S. Scholl, J. Repke, N. Gretz, H. Karbstein

ProcessNet: Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Membrantechnik und Mischvorgänge, München-Unterhaching

2018

Vortrag: "M2Aind-3D platforms"

Referent: Prof. Dr. Rüdiger Rudolf

3D-Mini-Symposium

Vortrag: "Kinetic measurements, online Spectroscopy, and Scale-Up in Micro Reactors"

Referent: Prof. Dr. Thorsten Röder

Kinetic measurements, online Spectroscopy, and Scale-Up in Micro Reactors

Vortrag: The Scale-Up of Reactions, Parametric Sensitivity and Online Analytics in Micro Reactor

Organic Process Research and Development, Mailand

Thorsten Röder

Vortrag: "Continuous Multiphase Reactions with Oxygen in Microstructured"

Referent: Prof. Dr. Thorsten Röder

Conference Politechnika Opolska, Uni Opeln, Polen

Vortrag: "Assessment of Alzheimer Amyloid Plaque Composition by MALDI Mass Spectrometry Imaging"

Referent: Prof. Dr. Carsten Hopf

Meeting of the GBM Study Group „Molecular Neurobiology“, Marburg

Vortrag: "Postnatal development of the interaction between sympathetic neurons and NMJs"

Referent: Prof. Dr. Rüdiger Rudolf

47th European Muscle Conference Budapest

Vortrag: "Sympathetic innervation of the NMJ; a possible explanation for the therapeutic effect of sympathicomimetics in NMDS?"

Referent: Prof. Dr. Rüdiger Rudolf

15th International Congress on Neuromuscular Diseases  Wien

Vortrag: "Einführung in das Thema "Nanostrukturen, Enzyme, Polymere"

Referent: Prof. Dr. Thorsten Röder, Teammitglied: Thorsten Baumeister

Kolloquium MDM - Nanostrukturen und Makromoleküle
BW Car, Stuttgart

Vortrag: "Kontaktlose Kinetikmessung im Tropfenreaktor mittels Raman"

Referent: Prof. Dr. Thorsten Röder, Teammitglied: Torsten Klement

SM²all – Mini Symposium zum Thema Prozessentwicklung und Prozessanalytik Hochschule Mannheim

Vortrag: "Chlormethan als Methylierungsmittel im kontinuierlichen Reaktor"

Referent: Prof. Dr. Thorsten Röder, Teammitglied: Clarissa Benzin

SM²all – Mini Symposium zum Thema Prozessentwicklung und Prozessanalytik Hochschule Mannheim

Vortrag: "European mini-symposium Let’s meet at the neuromuscular junction"

Referent: Prof. Dr. Rüdiger Rudolf

European mini-symposium Let’s meet at the neuromuscular junction Paris

Vortrag: "Einführung in das Thema „Aktuelle Methoden der biomedizinischen Massenspektrometrie"

Referent: Prof. Dr. Carsten Hopf

Kolloquium DuT - Massenspektrometrie 2
BW Car, Stuttgart

Vortrag: "Development of FT-MS assays and multimodal MALDI FT-MS imaging"

Referent: Prof. Dr. Carsten Hopf

13. EFTMS Tagung, Freising

Vortrag: "Applications of optical process spectroscopy in brewing processes"

Referent: Prof. Dr. Matthias Rädle

13th International Trends in Brewing

Vortrag: "MSI applications in diagnostics and pharmacology"

Referent: Prof. Dr. Carsten Hopf

WIMS #2 Workshop on Imaging Mass Spectrometry, Saint-Malo, Frankreich

Vortrag: "1) M²Aind Einführung, 2) HaCaT-Sphäroide und Swelling Experimente, 3) Themen und Methoden im Institut"

Referent: Prof. Dr. Rüdiger Rudolf

Symposium bei der BRAIN AG

Vortrag: "Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies"

Referent: Prof. Dr. Carsten Hopf, Teammitglieder: Rabe JH, A Sammour D, Schulz S, Munteanu B, Ott M, Ochs K, Hohenberger P, Marx A, Platten M, Opitz CA, Ory DS

European Mass Spectrometry Conference (EMSC) 2018, Saarbrücken

Vortrag: "Entwicklung eines Partikelmesssystems zur Erfassung sehr geringer Intensitäten zum Einsatz sehr schwacher Laser"

Referent: Prof. Dr. Matthias Rädle, Teammitglied: T. Teumer

Jahrestreffen Bremen - Jahrestreffen der ProcessNet Fachgruppen MPH, WSUE, CFD, HTT, AuW, KRI, PMT, Bremen

Vortrag: "Raman-Scanning zur Untersuchung fluidverfahrenstechnischer Vorgänge"

Referent: Prof. Matthias Rädle

ProcessNet: Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Membrantechnik und Mischvorgänge, München-Unterhaching

Vortrag: "Untersuchung von lokalen Konzentrationsverteilungen in Fluiden mit Hilfe der Nahinfrarot-Bildanalyse"

Referent: Prof. Dr. Matthias Rädle; Teammitglieder: I. Medina, M. Rädle, L. Schmitt, V. Kapoustina, S. Scholl

ProcessNet: Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Membrantechnik und Mischvorgänge, München-Unterhaching

Vortrag: Ultraschnelle lokale Ramanmessung zur Untersuchung von Mischvorgängen in Mikroreaktoren

ProcessNet: Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Membrantechnik und Mischvorgänge, München-Unterhaching

M. Rädle, J. Deuerling, S. Keck, F. Braun, M. Nachtmann, T. Hufnagel, L. Schmitt,
S. Scholl, J. Repke, N. Gretz, H. Karbstein

Vortrag: "Lipid/metabolite MSI for biomarker discovery and translational clinical research"

Referent: Prof. Dr. Carsten Hopf

Bruker Event mit M²Aind: MALDI Innovations in Pharma, Hochschule Mannheim, Mannheim

Vortrag: "Einführung in das Thema "Ramanspektroskopie"

Referent: Prof. Dr. Matthias Rädle

Kolloqium DuT - Ramanspektroskopie
BW Car, Stuttgart

Vortrag: "MSI Akquisition und Dateninterpretation von mittels FTIR definierten Gewebestrukturen"

Referent: Prof. Dr. Carsten Hopf, Teammitglied: Dr. Jan-Hinrich Rabe

Bruker Anwendertreffen Massenspektrometrie 2018, Berlin

Vortrag: "Kombination von Massenspektrometrie und Optischer Spektroskopie zur erweiterten Produktcharakterisierung im Bereich Biomedizin und Verfahrenstechnik"

Referent: Prof. Dr. Carsten Hopf

Gesprächskreis Rhein-Neckar
Pepperl + Fuchs Gmbh, Mannheim

Vortrag: "MALDI mass spectrometry assays and - imaging for drug profiling and spatially resolved PK-PD studie"

Referent: Prof. Dr. Carsten Hopf

Advances in Chemical Biology, Dechema Frankfurt

Hochschule Mannheim
M²Aind Projektkoordination
Paul-Wittsack-Strasse 10
68163 Mannheim

+49 621 292-6579
m2aind@hs-mannheim.de

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