Jahr 2022

Development and In Vitro Differentiation of Schwann Cells

Journal: Cells 2022 (11,23), https://doi.org/10.3390/cells11233753

Sarah Janice Hörner1,2,3, Nathalie Couturier1,2,3, Daniele Caroline Gueiber1,2,3,4, Mathias Hafner1,5, Rüdiger Rudolf1,2,3,5

1Institute of Molecular and Cell Biology, Mannheim University of Applied Sciences, 68163 Mannheim, Germany

2Interdisciplinary Center for Neurosciences, Heidelberg University, 69120 Heidelberg, Germany

3Center for Mass Spectrometry and Optical Spectroscopy, Mannheim University of Applied Sciences, 68163 Mannheim, Germany

4Department of Electronics Engineering, Federal University of Technology Paraná, Ponta Grossa 84017-220, Brazil

5Institute of Medical Technology, Heidelberg University and Mannheim University of Applied Sciences, 69117 Heidelberg, Germany

Deep-learning assisted data augmentation of spectral data for the authentication and quality analysis of food products

Journal: Lebensmittelchemie 76(S2):S2-181-S2-181, doi:10.1002/lemi.202259137

Sascha Rohn, Philipp Weller, Leslie Simon

Hochschule Mannheim, Paul-Wittsack-Straße 10, 68163 Mannheim

Influence of Refractive Index Differences on the Signal Strength for Raman-Spectroscopic Measurements of Double Emulsion Droplets

Journal: Applied Scienceshttps://doi.org/10.3390/app12189056

Thomas Hufnagel1, Matthias Rädle1, Heike P. Karbstein2

1CeMOS—Center for Mass Spectrometry and Optical Spectroscopy, Mannheim University of Applied Science, Paul-Wittsack-Straße 10, 68163 Mannheim, Germany

2Institute of Process Engineering in Life Science, Chair I: Food Process Engineering, Karlsruhe Institute of Technology, Kaiserstraße 12, 76131 Karlsruhe, Germany 

Prediction of Fluorescent Ki67 Staining in 3D Tumor Spheroids

Journal: Current Directions in Biomedical Engineering, Band 8 Heft 2, https://doi.org/10.1515/cdbme-2022-1078

Roman Bruch1, Mario Vitacolonna2, Rüdiger Rudolf2, Markus Reischl3

1Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany

2Center for Mass Spectrometry and Optical Spectroscopy (CeMOS) and Institute of Molecular and Cell Biology, Mannheim University of Applied Sciences, Mannheim, Germany

3Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany

Multivariate data analysis of low and high field NMR data of brewed coffee from fermented coffee beans

Journal: Lebensmittelchemie, Volume76, IssueS:  https://doi.org/10.1002/lemi.202259089

Catherine Kiefer1, Sascha Rohn2, Philipp Weller1

1HochschuleMannheim, Institut für Instrumentelle Analytik/Competency Center for Chemometrics CHARISMA, Mannheim, Germany

2TU Berlin, Institut für Lebensmittelchemie, Berlin, Germany

VOC-basiertes Profiling von Zitrusprodukten mittels GC-MS-IMS & maschinellem Lernen

Journal: Lebensmittelchemie 76(S2):S2-183-S2-184, doi:10.1002/lemi.202259139

L. Bodenbender2, P. Weller1, S. Rohn1

1HochschuleMannheim, Institut für Instrumentelle Analytik/Competency Center for Chemometrics CHARISMA, Mannheim, Germany

2TU Berlin, Institut für Lebensmittelchemie, Berlin, Germany

gc-ims-tools - A new Python package for chemometric analysis of GC-IMS data

Journal: Food Chemistry, Volume 394, https://doi.org/10.1016/j.foodchem.2022.133476

JoschaChristmann1,2 ,SaschaRohn2,3PhilippWeller1

1Institute for Instrumental Analytics and Bioanalysis, Mannheim University of Applied Sciences, Paul–Wittsack-Straße 10, 68163 Mannheim, Germany

2Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany

3Department of Food Chemistry and Analysis, Institute of Food, Technology and Food Chemistry, Technische Universität Berlin, TIB 4/3-1, Gustav-Meyer-Allee 25, 13355 Berlin, Germany

Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension

Journal: Journal of Flow Chemistry (2022), https://doi.org/10.1007/s41981-022-00224-2

Marcus Hafner1, Fabian Wolff1, Thorsten Röder1

1Institute of Chemical Process Engineering, Mannheim University of Applied Sciences, Paul-Wittsack-Straße 10, 68163, Mannheim, Germany

Marker-Free, Molecule Sensitive Mapping of Disturbed Falling Fluid Films Using Raman Imaging

Journal: Sensors 2022, 22(11), https://doi.org/10.3390/s22114086

Marcel Nachtmann1, Sebastian Sold1, Felix Wühler1, Stephan Scholl2, Matthias Rädle1

1Center for Mass Spectrometery and Optical Spectroscopy, Hochschule Mannheim University of Applied Sciences, 68163 Mannheim, Germany

2Institute for Chemical and Thermal Process Engineering, Technische Universität Braunschweig, 38106 Braunschweig, Germany

Traditional Grain-Based vs. Commercial Milk Kefirs, How Different Are They?

Journal: Applied Science https://doi.org/10.3390/app12083838

Fatemeh Nejati1, Charlotte C. Capitain2, Jannike Lea Krause3, Gi-Ung Kang3, René Riedel3, Hyun-Dong Chang3,4, Jens Kurreck5, Stefan Junne1, Philipp Weller2, Peter Neubauer1

1Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany

2Institute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany

3German Rheumatism Research Center Berlin, A Leibniz Institute—DRFZ, Schwiete Laboratory for Microbiota and Inflammation, 10117 Berlin, Germany

4Chair of Cytometry, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany

5Department of Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany

 

A new update of MALDI-TOF mass spectrometry in lipid research

Journal: Progress lipid Research, https://doi.org/10.1016/j.plipres.2021.101145

Kathrin M. Engel1, Patricia Prabutzki1, Jenny Leopold1, Ariane Nimptsch1, Katharina Lemmnitzer1, Naomi Vos2, Carsten Hopf2, Jürgen Schiller2

1Leipzig University, Faculty of Medicine, Institute for Medical Physics and Biophysics, Härtelstraße 16-18, D-04107, Germany

2Center for Biomedical Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul-Wittsack-Strasse 10, D-68163 Mannheim, Germany

Pesticide handling and waste management: a case study on DDT and HCHs from the Southern Caucasus

Journal: SN Applied Sciences, https://doi.org/10.1007/s42452-022-04999-w

Daniela Lud1, Annika Schwemm2, Besik Kalandadze3, Elbay Babaev4, Marcel Pierre Simon2, Philipp Weller5, Rolf-Alexander Düring2

1Faculty of Communication and Environment, Rhein-Waal University of Applied Sciences, Hochschule Rhein-Waal, Kamp-Lintfort, Germany

2Institute of Soil Science and Soil Conservation, Justus Liebig Universitat Giessen, Giessen, Germany

3Department of Soil Geography, Faculty of Exact and Natural Sciences, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia

4Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, Baku, Azerbaijan

5Institute of Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, Hochschule Mannheim, Mannheim, Germany

Volatilomics-Based Microbiome Evaluation of Fermented Dairy by Prototypic Headspace-Gas Chromatography–High-Temperature Ion Mobility Spectrometry (HS-GC-HTIMS) and Non-Negative Matrix Factorization (NNMF)

Journal: Metaboliteshttps://doi.org/10.3390/metabo12040299

Charlotte C. Capitain1, Fatemeh Nejati2, Martin Zischka1, Markus Berzak1, Stefan Junne2, Peter Neubauer2, Philipp Weller1

1Institute for Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, 68163 Mannheim, Germany

2Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Ackerstrasse 76 ACK 24, 13355 Berlin, Germany

3D Melanoma Cocultures as Improved Models for Nanoparticle-Mediated Delivery of RNA to Tumors

Journal: 10.3390/cells11061026 

Maximilian E. A. Schäfer1, Florian Keller1, Jens Schumacher2, Heinrich Haas2, Fulvia Vascotto3, Ugur Sahin2, Mathias Hafner1,4and Rüdiger Rudolf1,4,5

1Institute of Molecular and Cell Biology, Hochschule Mannheim, 68163 Mannheim, Germany

2Biopharmaceutical New Technology (BioNTech) SE, 55131 Mainz, Germany

3Translational Oncology (TRON), University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany

4Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Hochschule Mannheim, 68163 Mannheim, Germany 

VOC‐basiertes Profiling mittels GC‐(ITD)MS/MS‐IMS und maschinellem Lernen

Journal: Lebensmittelchemie Volume 76, Issue S1, https://doi.org/10.1002/lemi.202258013

L. Bodenbender1, P. Weller1, S. Rohn1

1Institute of Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, Hochschule Mannheim, Mannheim, Germany

Überwachung von Fermentationsprozessen durch Gaschromatographie-lonenmobilitätsspektrometrie (GC-IMS) und maschinelles Lernen

Journal: Lebensmittelchemie Volume 76, Issue S1, https://doi.org/10.1002/lemi.202258012

Joscha Christmann1,2, Sascha Rohn2,3, Philipp Weller1

1Institute for Instrumental Analytics and Bioanalysis, Mannheim University of Applied Sciences, Paul-Wittsack-Straße 10, 68163Mannheim, Germany

2Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany

3Department of Food Chemistry and Analysis, Institute of Food, Technology and Food Chemistry, Technische Universität Berlin, TIB 4/3-1, Gustav-Meyer-Allee 25, 13355 Berlin, Germany

Deep‐learning assistierte Datenaugmentierung spektraler Daten zur Authentifizierung und Qualitätskontrolle von Lebensmitteln

Journal: Lebensmittelchemie Volume 76, Issue S1,  https://doi.org/10.1002/lemi.202258011

Leslie Simon1,Sascha Rohn2, Philipp Weller1

1Hochschule Mannheim, Institut für Instrumentelle Analytik, Mannheim, Germany

2TU Berlin, Institut für Lebensmittelchemie, Berlin, Germany

LPS‑induced lipid alterations in microglia revealed by MALDI mass spectrometry‑based cell fingerprinting in neuroinflammation studies

Journal: Nature Research (2022)

Martina Blank1,2*, Thomas Enzlein1, Carsten Hopf1,3

1Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul‑Wittsack Str. 10, 68163 Mannheim, Germany.

2Structural Molecular Biology Laboratory (LABIME), Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, SC 88040‑900, Brazil.

3Medical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany.