Jahr 2018
Development of a particle measuring system for recording the scattered light intensities, optimized for the use of very weak laser beams
Journal: Chemie Ingenieur Technik, doi: https://doi.org/10.1002/cite.201800073
T. Teumer1, T. Hufnagel1,,*, T. Schäfer1, R. Schlarp‐Horvath1, H.P. Karbstein2, F.J. Methner3, M. Rädle1
*M2Aind-PhD Student, Technische Hochschule Mannheim, Paul-Wittsack-Str. 10, 68163 Mannheim/Germany
1Technische Hochschule Mannheim, CeMOS – Center of mass spectrometry and optical spectroscopy, Paul-Wittsack-Straße 10, 68163 Mannheim, Deutschland.
2KIT, Institut für Bio- und Lebensmitteltechnik, Teilinstitut I: Lebensmittelverfahrenstechnik, Kaiserstraße 12, 76131 Karlsruhe, Deutschland.
3Technische Universita¨t Berlin, Institut für Lebensmitteltechnologie und Lebensmittelchemie, Fachgebiet Brauwesen, Straße des 17. Juni 135, 10623 Berlin, Deutschland.
Site-to-Site Reproducibility and Spatial Resolution in MALDI-MSI of Peptides from Formalin-Fixed Paraffin-Embedded Samples
Journal: Proteomics Clinical Applications, doi: https://doi.org/10.1002/prca.201800180
A. Ly5, R. Longuespée6, R. Casadonte1, P. Wandernoth1, K. Schwamborn2, Ch. Bollwein2, Ch. Marsching3, K. Kriegsmann4, C. Hopf3, W. Weichert2, J. Kiregsmann1, P. Schirmacher6, M. Kriegsmann6, S.-O. Deininger5
1Proteopath GmbH, Trier, Germany.
2Institute of Pathology Technical University of Munich Munich, Germany.
3Center for Biomedical Mass Spectrometry and Optical Spectroscopy (CeMOS), Technische Hochschule Mannheim, Mannheim, Germany.
4Department of Hematology Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
5Bruker Daltonik GmbH, Bremen, Germany.
6Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
A customized stand-alone photometric Raman sensor applicable in explosive atmospheres: a proof-of-concept study
Journal: Journal of Sensor and Sensor Systems, doi.org/10.5194/jsss-7-543-2018
M. Nachtmann1, S.P. Keck1,*, F. Braun1, H. S. Eckhardt2, Chr. Mattolat2, N. Gretz3, St. Scholl4, M. Rädle1
1Institute for Process Control and Innovative Energy Conversion, Technische Hochschule Mannheim, Mannheim, 68163, Germany.
2tec5 AG, Oberursel/Ts, 61440, Germany.
3Medical Research Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany.
4Institute for Chemical and Thermal Process Engineering, Technical University Braunschweig, Braunschweig, 38106, Germany.
*M2Aind-PhD Student, Technische Hochschule Mannheim, Paul-Wittsack-Str. 10, 68163 Mannheim/Germany
Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development.
Journal: Current Opinion in Biotechnology, doi: https://doi.org/10.1016/j.copbio.2018.08.003
S. Schulz1, M. Becker2, M. Reid Groseclose3, S. Schadt4, C. Hopf1
1Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Technische Hochschule Mannheim, Mannheim, Germany
2Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach/Riss, Germany
3Bioimaging US, GlaxoSmithKline, King of Prussia, PA 19406, United States
4Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland
Automated analysis of lipid drug-response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping.
Journal: Scienetific Reports, doi.org/10.1038/s41598-018-29677-z
D. Weigt1,2, D. A. Sammour1, T. Ulrich1, B. Munteanu1, C. Hopf1,2
1Center for biomedical Mass Spectrometry and Optical Spectroscopy (CeMOS), Technische Hochschule Mannheim, Paul-Wittsack Str. 10, 68163, Mannheim, Germany.
2HBIGS International Graduate School of Molecular and Cellular Biology, Heidelberg University, Im Neuenheimer Feld 501, 69120, Heidelberg, Germany.
Postnatal Development and Distribution of Sympathetic Innervation in Mouse Skeletal Muscle
Journal: International Journal of Molecular Sciences, doi: 10.3390/ijms19071935
T. Straka1,2,3, V. Vita4, K. Prokshi1,2, S. J. Hörner1,2,*, M.M. Khan1,2,3, M. Pirazzini4, M.P.I. Williams1,M. Hafner1, T. Zaglia4,5,6, R. Rudolf1,2,3,7
1Institute of Molecular and Cell Biology, Technische Hochschule Mannheim, 68163 Mannheim, Germany.
2Interdisciplinary Center for Neurosciences, Heidelberg University, 69120 Heidelberg, Germany.
3Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, 76344 Eggenstein-Leopoldshafen, Germany.
4Venetian Institute of Molecular Medicine, 35129 Padua, Italy.
5Department of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
6Department of Cardiac Thoracic and Vascular Sciences, University of Padua, 35128 Padua, Italy.
7Author to whom correspondence should be addressed.
*M2Aind-PhD Student, Technische Hochschule Mannheim, Paul-Wittsack-Str. 10, 68163 Mannheim/Germany
Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer’s Disease
Journal: Frontiers in Molecular Neuroscience, doi: https://doi.org/10.3389/fnmol.2018.00206
S. Herzer1,2, C. Hagan1,3, J. von Gerichten1,4, V. Dieterle1,2, B. Munteanu5, R. Sandhoff1,4, C. Hopf5, V. Nordström1,2*
1Division of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.
2Interdisciplinary Center for Neurosciences, Heidelberg University, Heidelberg, Germany.
3Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.
4Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany.
5Center for Mass Spectrometry (CeMOS), University of Heidelberg and Technische Hochschule Mannheim, Mannheim, Germany.
Volatile-Compound Fingerprinting by Headspace-Gas-Chromatography Ion-Mobility Spectrometry (HS-GC-IMS) as a Benchtop Alternative to 1H NMR Profiling for Assessment of the Authenticity of Honey.
Journal: Analytical Chemistry, doi.org/10.1021/acs.analchem.7b03748
N. Gerhardt1, M. Birkenmeier1, S. Schwolow2, S. Rohn1, P. Weller1
1Institute for Instrumental Analytics and Bioanalysis, Technische Hochschule Mannheim, 68163 Mannheim, Germany.
2Hamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, 20146 Hamburg, Germany.